产品货号：
Z32381
中文名称：
ARHGEF4 Purified抗体
英文名称：
Anti-ARHGEF4 Purified Antibody (Clone#ARHGEF-08)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ARHGEF4 Purified Antibody (Clone#ARHGEF-08) |
| 指标别名 | ARHGEF4,ASEF,ASEF1,GEF4,KIAA1112,STM6 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,WB |
| 基因名称 | ARHGEF4 |
| 克隆号 | ARHGEF-08 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Recombinant fragment of human ARHGEF4 (amino acids 143-271).The mouse monoclonal antibody ARHGEF-08 recognizes human intracellular protein ARHGEF4/ASEF1,approx.80kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42.The epitope is located in the rough at the region of SH3 domain. |
| 计算分子量 | 79kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | ARHGEF4 (Rho guanine nucleotide exchange factor 4),also known as ASEF 1 (adenomatous polyposis coli每;stimulated guanine nucleotide exchange factor 1) is an approximately 80kDa cytoplasmic protein important for growth factor-mediated regulation of cell morphology and migration.Besides N-terminal adenomatous polyposis coli (APC)-binding region (ABR) it contains Dbl homology (DH),pleckstrin homology (PH) and SH3 domains.The SH3 domain inhibits GEF activity of ARHGEF4 by intramolecular interaction with the DH domain,whereas binding of APC stimulates the GEF activity.Activated ARHGEF4 stimulates the small GTPase Cdc42,which leads to decreased cell-cell adherence and enhanced cell migration. |
| Uniprot ID | Q9NR80 |
| 基因名全称 | Rho guanine nucleotide exchange factor 4 |
| 蛋白名全称 | Rho guanine nucleotide exchange factor 4 |
| 推荐稀释比 | Flow cytometry:1～4μg/mL.Intracellular staining. |
相关搜索：ARHGEF4 Purified抗体，ARHGEF4 Purified单抗，Anti-ARHGEF4 Purified Antibody (Clone#ARHGEF-08)